학술논문

Sex Differences in Presentation, Treatment Patterns, and Clinical Outcomes in Central Retinal Vein Occlusion
Document Type
Clinical report
Source
Ophthalmic Surgery, Lasers, and Imaging Retina. May, 2020, Vol. 51 Issue 5, p279, 7 p.
Subject
Medical research
Medicine, Experimental
Language
English
ISSN
2325-8160
Abstract
BACKGROUND AND OBJECTIVE: To evaluate the impact of sex differences on the presenting features, treatment patterns, and clinical outcomes in patients with central retinal vein occlusions (CRVO). PATIENTS AND METHODS: This retrospective, longitudinal cohort study included 476 patients diagnosed with CRVO over a 7-year period. Charts were reviewed and clinical data were abstracted. RESULTS: The average age at CRVO onset was lower in males (63.8 years vs. 66.1 years; P =.048). More males (104/224, 54%) had an ischemic CRVO compared to females (113/252, 45%) at 12 months (P =.05). Males with CRVO had a greater central subfield thickness at the baseline (546.7 ± 306.8 μm vs. 438.4 ± 252.9 μm; P =.003) and final visits (343 ± 179.5 μm vs. 304.6 ± 176.2 μm; P =.005). Foveal avascular zone enlargement was more likely in males (39/102, 38% vs. 29/116, 25%; P =.04). CONCLUSIONS: Sex differences exist in presenting features of patients with CRVO. Further inquiry may help provide individualized recommendations for management of CRVO. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:279–285.]
Introduction Retinal vein occlusion (RVO) is a retinal vascular disorder that can result in profound vision loss secondary to macular edema and retinal ischemia. (1) Subtypes of RVO include central [...]