학술논문
Frequency of the codon 807 mutation in the cGMP phosphodiesterase beta-subunit gene in Irish setters and other dog breeds with hereditary retinal degeneration
Document Type
Academic Journal
Author
Source
The Journal of Heredity. Jan-Feb, 1999, Vol. 90 Issue 1, p143, 5 p. 3
Subject
Language
ISSN
0022-1503
Abstract
A study was conducted to analyze the frequency of the codon 807 mutation in the cGMP phosphodiesterase beta-subunit gene in Irish setters and other dog breeds with hereditary retinal degeneration. Blood samples were obtained in anticoagulant tubes or retrieved from the archival tissue samples. A mismatch primer was then utilized to amplify partial canine exon. Results indicated the importance of molecular diagnostic test to identify Irish setter dogs at risk to be carriers for rod-cone dysplasia 1.