부산대학교 도서관

To authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1399-3062.2009.00386.x Byline: J.M. Huston (1), P.S. Barie (1,2), S.R. Eachempati (1,2), J.R. Rodney (1), C. Cayci (1), D. Fusco (3), M. Mathew (4), J. Shou (1), M.J. Goldstein (5), S. Kapur (5) Keywords: renal transplantation; drotrecogin alfa (activated); Strongyloides stercoralis; severe sepsis; ivermectin Abstract: Abstract: We report a case of Strongyloides stercoralis hyperinfection syndrome in a renal transplant recipient complicated by septic shock, acute respiratory distress syndrome, and Klebsiella pneumoniae superinfection. The patient was treated successfully with drotrecogin alfa (activated), parenteral ivermectin, albendazole, and piperacillin/tazobactam. This outcome suggests that drotrecogin alfa (activated) may be useful therapy for transplant recipients who develop severe sepsis or septic shock secondary to potentially lethal opportunistic infections. Author Affiliation: (1)Department of Surgery, Division of Critical Care and Trauma (2)Department of Public Health (3)Department of Medicine, Division of Infectious Diseases (4)Department of Pharmacy (5)Department of Surgery, Division of Transplantation, New York Presbyterian Hospital, Weill Cornell Medical College, New York, New York, USA Article History: Received 24 December 2008, revised 20 February 2009, accepted for publication 23 February 2009 Article note: Correspondence to:, Philip S. Barie, MD, MBA, Department of Surgery, Division of Critical Care and Trauma, New York Presbyterian Hospital, Weill Cornell Medical College, 525 East 68 Street, New York, NY 10065, USA, Tel: 212 746 5401, Fax: 212 746 6995, E-mail: pbarie@med.cornell.edu