학술논문
Biclonal post-transplant B-cell lymphoma: report of a case with two distinct cell populations, XX,t(14;18) and XY,t(11;14)
Document Type
Author abstract
Author
Source
Cancer Genetics and Cytogenetics. March, 2007, Vol. 173 Issue 2, p150, 4 p.
Subject
Language
English
ISSN
0165-4608
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.cancergencyto.2006.09.020 Byline: Katie L. Dennis (a), Steven L. Wallentine (b), Peter J. Vanveldhuizen (b), Diane L. Persons (a), Sharad C. Mathur (a) Abstract: Lymphoproliferative disorders are more likely to occur in transplant patients compared to the general population. Typically in these patients, lymphomas occur within 6-10 months following transplant and are Epstein-Barr virus (EBV) positive. We report a biclonal apparently EBV negative lymphoma occurring in a patient ten years after renal transplant, with karyotypes XX,t(14;18) and XY,t(11;14). Though the biclonal populations also had different sex chromosome compositions, complete evaluation showed that both clones most likely evolved from the patient's native lymphocytes. Author Affiliation: (a) Department of Pathology and Laboratory Medicine, University of Kansas Medical Center/Kansas City VA Medical Center, 4801 Linwood Boulevard, Kansas City, Missouri 64128 (b) Division of Medical Oncology and Hematology, Department of Internal Medicine, University of Kansas Medical Center/Kansas City VA Medical Center, 4801 Linwood Boulevard, Kansas City, Missouri 64128 Article History: Received 11 August 2006; Revised 19 September 2006; Accepted 27 September 2006