학술논문
p73alpha is a candidate effector in the p53 independent apoptosis pathway of cisplatin damaged primary murine colonocytes
Document Type
Academic Journal
Author
Source
Journal of Clinical Pathology. May, 2004, Vol. 57 Issue 5, p492, 7 p.
Subject
Language
English
ISSN
0021-9746
Abstract
p53 mediated apoptosis and growth arrest are not the only means by which colonic murine epithelial cells guard against mutation after DNA damage. The endogenous p73alpha was translocated to the nucleus in response to DNA damage in primary murine colonocytes, which suggests a functional proapoptotic role for p73alpha in p53 deficient cells.