학술논문
Potential New Therapeutic Implications of Semaglutide: New Colours of the Rainbow?
Commentary
Commentary
Document Type
Academic Journal
Source
Diabetes Therapy. January 2024, Vol. 15 Issue 1, p13, 6 p.
Subject
Language
English
ISSN
1869-6953
Abstract
Author(s): Evanthia Gouveri [sup.1], Djordje S. Popovic [sup.2] [sup.3], Nikolaos Papanas [sup.1] Author Affiliations: (1) grid.412483.8, 0000 0004 0622 4099, Diabetes Centre, Second Department of Internal Medicine, Democritus University of [...]
Semaglutide is a potent glucagon-like peptide 1 receptor agonist for the management of type 2 diabetes mellitus. In addition to this, it has emerging potential clinical implications. First, there is accumulating preliminary data on its potential role in type 1 diabetes mellitus. In this setting, we need to know which patient subgroups may benefit more. Furthermore, its role in non-alcoholic fatty liver and in non-alcoholic steatohepatitis is emerging. Other potential therapeutic implications of semaglutide include kidney disease, Alzheimer disease and pulmonary diseases. Nonetheless, we still need much more information on its long-term efficacy, safety and utility in these new implications before any definitive conclusions may be drawn for everyday practice.
Semaglutide is a potent glucagon-like peptide 1 receptor agonist for the management of type 2 diabetes mellitus. In addition to this, it has emerging potential clinical implications. First, there is accumulating preliminary data on its potential role in type 1 diabetes mellitus. In this setting, we need to know which patient subgroups may benefit more. Furthermore, its role in non-alcoholic fatty liver and in non-alcoholic steatohepatitis is emerging. Other potential therapeutic implications of semaglutide include kidney disease, Alzheimer disease and pulmonary diseases. Nonetheless, we still need much more information on its long-term efficacy, safety and utility in these new implications before any definitive conclusions may be drawn for everyday practice.