부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.nimb.2005.08.081 Byline: P. Yang (a)(b), N. Huang (a), Y.X. Leng (a), Z.Q. Yao (a), H.F. Zhou (a), M. Maitz (c), Y. Leng (d), P.K. Chu (b) Keywords: Plasma immersion ion implantation-deposition (PIII-D); Nitrogen-doped hydrogenated amorphous carbon (a-C:H:N); Wettability; Biocompatibility Abstract: Amorphous carbon films have been applied in biomedical fields as potential biocompatible materials with wettability that can be adjusted by doping with other elements, including F, Si, Ti, O and N. In this study, nitrogen-doped hydrogenated amorphous carbon (a-C:H:N) films were deposited by PIII-D using C.sub.2H.sub.2 +N.sub.2 gas mixtures. The biocompatibility and anti-thrombotic properties of the films were assessed in vitro. The surface morphology and surface wettability of the films were characterized using atomic force microscopy (AFM) and a contact angle method. The results show no cytotoxicity for all films, and films with appropriate nitrogen doping possess much better endothelial cell growth and anti-thrombotic properties. Author Affiliation: (a) Laboratory of Surface Modification of Artificial Organs of Sichuan, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, Sichuan 610031, China (b) Department of Physics and Materials Science, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China (c) Institute of Ion Beam Physics and Materials Research, Forschungszentrum Rossendorf e.V., P.O. Box 510119, 01314 Dresden, Germany (d) Department of Mechanical Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China