학술논문
Identification of Differentially Expressed Genes in Papillary Thyroid Carcinomas With and Without Rearrangements of the Tyrosine Kinase Receptors RET and/or NTRK1.sup.1 1 This work was supported by a grant of the Deutsche Forschungsgemeinschaft to T.J.M. (MU 1221/5-1) and, in part, by a cash prize of the Lower Saxony Cancer Society (Forderpreis der Niedersachsischen Krebsgesellschaft) to P.B.M. and T.J.M
Document Type
Report
Author
Source
Journal of Surgical Research. March, 2006, Vol. 131 Issue 1, p15, 11 p.
Subject
Language
English
ISSN
0022-4804
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jss.2005.08.013 Byline: Thomas J. Musholt ([cor]), Christoph Brehm, Julia Hanack, Reinhard von Wasielewski, Petra B. Musholt ([cor]) Keywords: papillary thyroid carcinoma; differential gene expression; chromosomal rearrangements; genetic alterations; mRNA differential display Abstract: The transforming capacities of RET and/or NTRK1 chimeric oncogenes as well as the molecular background of non-rearranged papillary thyroid carcinomas (PTCs) remain to be elucidated. To assess altered gene expression, we examined PTCs with and without tyrosine kinase receptor rearrangements by mRNA differential display (DD). Author Affiliation: ([cor]) Endocrine Surgery, Johannes Gutenberg University Mainz, Mainz, Germany (a ) Visceral and Transplantation Surgery, Hannover University Medical School, Hannover, Germany (a ) Pathology, Hannover University Medical School, Hannover, Germany Article History: Received 11 April 2005