학술논문
Relative acidities of ortho-substituted phenols, as models for modified tyrosines in proteins
Document Type
Academic Journal
Source
Journal of Physical Chemistry A. Sept 19, 2002, Vol. 106 Issue 37, 8757-8761
Subject
Language
English
ISSN
1089-5639
Abstract
The examination of the effects of a variety of ortho-substituents on the acidity of phenol is presented. The substitutions are made at the ortho-position to model modified tyrosine residues found in enzymes and a comparison of the substituent effects on the O--H bond strengths and the acidities indicate no simple correlation between the two.