학술논문
Influence of Humic Acids Isolated from Raised Bog Sphagnum Peat on Development of Th1/Th2 Immune Response
Document Type
Academic Journal
Author
Source
Bulletin of Experimental Biology and Medicine. December, 2022, Vol. 174 Issue 2, p236, 5 p.
Subject
Language
English
ISSN
0007-4888
Abstract
The course administration of humic acids isolated with sodium pyrophosphate from raised bog sphagnum peat reduces the parameters of a Thl-type immune response in C57BL/6 mice, the severity of an anaphylactic shock in outbred CD1 mice, and degranulation of mast cells after their immunization with ovalbumin. The addition of humic acids increases the stimulated production of IL-4, IL-10 and reduces the production of IL-2, IFN[gamma] by peripheral blood mononuclear cells of healthy donors. Key Words: humic acids; immune response; cytokines; anaphylaxis; mast cell degranulation
It is known that the effective immune response depends on the orchestrated functioning of various cells of innate and/or adaptive immunity, in which T helpers (CD4) occupy a special place. [...]
It is known that the effective immune response depends on the orchestrated functioning of various cells of innate and/or adaptive immunity, in which T helpers (CD4) occupy a special place. [...]