학술논문

Physical activity and cognitive function in adults born very preterm or with very low birth weight-an individual participant data meta-analysis
Document Type
Academic Journal
Source
PLoS ONE. February 13, 2024, Vol. 19 Issue 2, e0298311
Subject
Finland
Language
English
ISSN
1932-6203
Abstract
Objective Individuals born very preterm ( Study design Cohorts with data on physical activity and cognitive function in adults born very preterm/very low birth weight and term-born controls were recruited from the Research on European Children and Adults Born Preterm, and the Adults Born Preterm International Collaboration Consortia. A systematic literature search was performed in PubMed and Embase. Results Five cohorts with 1644 participants aged 22-28 years (595 very preterm/very low birth weight and 1049 controls) were included. Adults born very preterm/very low birth weight reported 1.11 (95% CI: 0.68 to 1.54) hours less moderate to vigorous physical activity per week than controls, adjusted for cohort, age and sex. The difference between individuals born very preterm/very low birth weight and controls was larger among women than among men. Neither intelligence quotient nor self-reported executive function mediated the association between very preterm/very low birth weight and moderate to vigorous physical activity. Results were essentially the same when we excluded individuals with neurosensory impairments. Conclusion Adults born very preterm/very low birth weight, especially women, reported less moderate to vigorous physical activity than their term-born peers. Cognitive function did not mediate this association. Considering the risk of adverse health outcomes among individuals born preterm, physical activity could be a target for intervention.
Author(s): Kristina Anna Djupvik Aakvik 1,*, Silje Dahl Benum 1, Marjaana Tikanmäki 2,3, Petteri Hovi 3,4, Katri Räikkönen 5, Sarah L. Harris 6, Lianne J. Woodward 7, Brian A. Darlow [...]