학술논문
Binding of cationic porphryrin to isolated DNA and nucleoprotein complex: Quantitative analysis of binding forms under various experimental conditions
Document Type
Academic Journal
Source
Biochemistry. Nov 15, 2005, Vol. 44 Issue 45, p15000, 7 p.
Subject
Language
English
ISSN
0006-2960
Abstract
A complex formation of tetrakis(4-n-methlypyridyl)porphyrin (TMPyP) with double stranded DNAs and T and phage nucleoprotein complex is presented. It shows that transition metals significantly decrease the binding sites for intercatation in both DNA and nucleoprotein complex, but facilitate the groove-binding of TMPyP to isolated DNA.