학술논문

Late onset of severe grafta[euro]versusa[euro]host disease following liver transplantation
Document Type
Academic Journal
Source
Transplant Immunology. Nov, 2006, Vol. 16 Issue 3-4, p250, 4 p.
Subject
Donation of organs, tissues, etc. -- Health aspects
Liver cancer -- Health aspects
Liver -- Transplantation
Liver -- Health aspects
Language
English
ISSN
0966-3274
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.trim.2006.08.006 Byline: Beicheng Sun, Chaochen Zhao, Yongxiang Xia, Guoqiang Li, Feng Cheng, Jun Li, Feng Zhang, Xuehao Wang Keywords: GVHD; Liver transplantation; Diarrhea; Pathology Abstract: Graft versus host disease (GVHD) is an uncommon but lethal complication following liver transplantation that results from the engraftment of T lymphocytes associated with the liver graft. It usually occurs 2 to 6 weeks after the procedure. We herein report a case of late onset of severe GVHD 4 months after cadaveric liver transplantation for hepatocellular carcinoma in a 54ayearaold woman, which was characterized by refractory diarrhea and abdominal pain. Moreover we discuss risk factors of GVHD including the recipient age and cytomegalovirus (CMV) infection. Author Affiliation: National Institute of Living Donor Liver Transplantation, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu 210029, P.R. China Article History: Received 31 May 2006; Revised 11 July 2006; Accepted 3 August 2006