학술논문
Current status of acne vaccines
Document Type
Academic Journal
Author
Source
Expert Review of Dermatology. October 2010, Vol. 5 Issue 5, p561, 6 p.
Subject
Language
English
ISSN
1746-9872
Abstract
Acne vulgaris is one of the most common diseases in the industrialized world, especially among teenagers and young adults. The disease is caused by many factors, such as elevated sebum, hyperkeratinization, hormonal changes and inflammation. A major player in the inflammatory component of acne is Propionibacterium acnes (P. acnes), and is associated with more moderate or severe forms of acne. Currently, the treatments for acne have several clinical, practical and financial disadvantages. Using P. acnes as a target, however, several studies have demonstrated the potential for a vaccine that would be able to prevent the onset of acne vulgaris, or at the very least reduce its severity to only a fraction of what it would be normally.
Author(s): Timothy Yen [sup.1] , Cheng-Yin Yuan [sup.1] , Chun-Ming Huang [sup.[[dagger]]] [sup.2] Keywords: acne vulgaris; compliance; dermis-based cell-trapped system; preventative vaccine; Propionibacterium acnes; sialidase; therapeutic vaccine; vaccine Pathogenesis of [...]
Author(s): Timothy Yen [sup.1] , Cheng-Yin Yuan [sup.1] , Chun-Ming Huang [sup.[[dagger]]] [sup.2] Keywords: acne vulgaris; compliance; dermis-based cell-trapped system; preventative vaccine; Propionibacterium acnes; sialidase; therapeutic vaccine; vaccine Pathogenesis of [...]