학술논문

Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins
Document Type
Report
Source
Journal of Biomolecular NMR. April, 2009, Vol. 43 Issue 4, p255, 5 p.
Subject
Dextrose
Glucose
RNA
Proteins
Language
English
ISSN
0925-2738
Abstract
GSP13 encoded by gene yugI is a [sigma].sup.B-dependent general stress protein in Bacillus subtilis, which can be induced by heat shock, salt stress, ethanol stress, glucose starvation, oxidative stress and cold shock. Here we report the solution structure of GSP13 and it is the first structure of S1 domain containing protein in Bacillus subtilis. The structure of GSP13 mainly consists of a typical S1 domain along with a C-terminal 50-residue flexible tail, different from the other known S1 domain containing proteins. Comparison with other S1 domain structures reveals that GSP13 has a conserved RNA binding surface, and it may function similarly to cold shock proteins in response to cold stress.