학술논문
Effectiveness and Power of Abdominal Ultrasonography in the Assessment of Crohn's Disease Activity: Comparison with Clinical, Endoscopic, and CT Enterography Findings
ORIGINAL ARTICLE
ORIGINAL ARTICLE
Document Type
Report
Author
Source
The Turkish Journal of Gastroenterology. April 2022, Vol. 33 Issue 4, p294, 10 p.
Subject
Language
English
ISSN
1300-4948
Abstract
INTRODUCTION Crohn's disease (CD) is a chronic inflammatory disease that can involve the whole gastrointestinal system (GIS), primarily the small intestine and the terminal ileum, and it progresses with stages [...]
Background: Non-invasive methods play an important role in clinical assessment of Crohn's disease. Recent studies have highlighted the effectiveness and reliability of intestinal ultrasonography. We aimed to examine the relationship between intestinal ultrasonography and the clinical, endoscopic, and computed tomography enterography findings, and to assess the activity of Crohn's disease. Methods: This was a 1-year prospective study involving patients diagnosed with Crohn's Disease. Clinical and endoscopic activity indices, and intestinal ultrasonography and computed tomography enterography findings were evaluated. Intestinal wall thickness, mesenteric inflammation, lymphadenopathy, and complications were evaluated by intestinal ultrasonograpy and computed tomography enterography, while the superior mesenteric artery flow velocity, resistive index, and Limberg score were assessed by Doppler intestinal ultrasonography. Results: Seventy-nine patients with Crohn's disease were included. A significant correlation was found between intestinal wall thickness, mesenteric inflammation, and complications in intestinal ultrasonography and computed tomography enterography (P = .0001). According to the receiver operating curve analysis, the intestinal wall thickness, and mesenteric inflammation were correlated with the Crohn's Disease Activity Index, Harvey-Bradshaw Index, and SES-CD scores (P < .05), and they were very effective in distinguishing active from inactive disease. According to the Crohn's Disease Activity Index and SES-CD scores, Doppler flow velocity of the superior mesenteric artery was significantly higher in the active group than in the inactive group (P < .05). The Limberg score was very consistent with the Crohn's Disease Activity Index, Harvey-Bradshaw Index , and the results of the Simple Endoscopic Score for Crohn's Disease (P < .0001). Conclusion: Our study showed that intestinal ultrasonography is an effective and reliable method for assessment of Crohn's disease activity compared to clinical, endoscopic, and CTE findings. Keywords: Computed tomography, Crohn's disease, enterography, intestinal ultrasonography
Background: Non-invasive methods play an important role in clinical assessment of Crohn's disease. Recent studies have highlighted the effectiveness and reliability of intestinal ultrasonography. We aimed to examine the relationship between intestinal ultrasonography and the clinical, endoscopic, and computed tomography enterography findings, and to assess the activity of Crohn's disease. Methods: This was a 1-year prospective study involving patients diagnosed with Crohn's Disease. Clinical and endoscopic activity indices, and intestinal ultrasonography and computed tomography enterography findings were evaluated. Intestinal wall thickness, mesenteric inflammation, lymphadenopathy, and complications were evaluated by intestinal ultrasonograpy and computed tomography enterography, while the superior mesenteric artery flow velocity, resistive index, and Limberg score were assessed by Doppler intestinal ultrasonography. Results: Seventy-nine patients with Crohn's disease were included. A significant correlation was found between intestinal wall thickness, mesenteric inflammation, and complications in intestinal ultrasonography and computed tomography enterography (P = .0001). According to the receiver operating curve analysis, the intestinal wall thickness, and mesenteric inflammation were correlated with the Crohn's Disease Activity Index, Harvey-Bradshaw Index, and SES-CD scores (P < .05), and they were very effective in distinguishing active from inactive disease. According to the Crohn's Disease Activity Index and SES-CD scores, Doppler flow velocity of the superior mesenteric artery was significantly higher in the active group than in the inactive group (P < .05). The Limberg score was very consistent with the Crohn's Disease Activity Index, Harvey-Bradshaw Index , and the results of the Simple Endoscopic Score for Crohn's Disease (P < .0001). Conclusion: Our study showed that intestinal ultrasonography is an effective and reliable method for assessment of Crohn's disease activity compared to clinical, endoscopic, and CTE findings. Keywords: Computed tomography, Crohn's disease, enterography, intestinal ultrasonography