학술논문
Human chromosomal localization of genes encoding the gamma-1 and gamma-2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome
Document Type
Academic Journal
Author
Source
Proceedings of the National Academy of Sciences of the United States. July 1, 1992, Vol. 89 Issue 13, p5857, 5 p.
Subject
Language
ISSN
0027-8424
Abstract
The genes coding for the human gamma-1 and gamma-2 subunits of the gamma-aminobutyric acid (GABA) receptor were mapped to chromosomes 4 and 5. Further deletion mapping showed that the gamma-1 and gamma-2 genes are located at the 4p14-q21.1 and 5q31.1-q33.2 regions, respectively. These regions correspond to the map locations of previously mapped GABA receptor genes. These results indicate that members of the GABA receptor gene family are organized in nonrandom gene clusters distributed widely in the human genome.