학술논문

Intrapartum tenofovir and emtricitabine reduces low-concentration drug resistance selected by single-dose nevirapine for perinatal HIV prevention
Document Type
Report
Source
AIDS Research and Human Retroviruses. Nov, 2009, Vol. 25 Issue 11, p1099, 8 p.
Subject
United States
Zambia
Language
English
ISSN
0889-2229
Abstract
A single dose of tenofovir/emtricitabine (TDF/FTC) during labor significantly reduces peripartum nevirapine-associated viral drug resistance when measured by consensus HIV sequencing. It is unknown whether this effect extends to HIV subpopulations of
Introduction Although effective in reducing mother-to-child transmission of HIV, peripartum single-dose nevirapine (NVP) has been associated with nonnucleoside reverse transcriptase inhibitor (NNRTI) viral drug resistance in the weeks following ingestion. [...]