학술논문

VALIDATION OF THE BRIEF INTERNATIONAL COGNITIVE ASSESSMENT FOR MULTIPLE SCLEROSIS (BICAMS) IN A LARGE COHORT OF RELAPSING-REMITTING MS PATIENTS
Document Type
Academic Journal
Source
Acta Clinica Croatica. March 2022, Vol. 61 Issue 1, p62, 8 p.
Subject
Batteries
Somatotropin
Recurrence (Disease)
Multiple sclerosis
Diseases -- Relapse
Language
English
ISSN
0353-9466
Abstract
Introduction Cognitive impairment is one of the most frequently reported symptoms that has significant impact on the working status of persons with multiple sclerosis (MS), responsible for their early retirement [...]
Cognitive impairment is one of the most frequently reported symptoms in persons with multiple sclerosis (MS). The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) has been recommended as a standardized international screening and monitoring tool for brief cognitive assessment. The aim of our study was to assess the reliability and validity of the Serbian version of the BICAMS. A total of 500 relapsing-remitting MS (RRMS) patients and 69 age-, gender- and education-matched healthy control (HC) subjects were examined. All participants performed the BICAMS test battery, which includes the oral version of the Symbol Digit Modalities Test (SDMT), California Verbal Learning Test second edition (CVLT-II), and Brief Visuospatial Memory Test Revised (BVMTR). A randomly selected subset of patients were retested one to three weeks after baseline. Statistically significant differences between patients and HCs were evident on the SDMT and BVMTR (p Key words: Multiple sclerosis; BICAMS; Cognition; Cognitive impairment; Validation