부산대학교 도서관

Natural tapering of coronary arteries from larger proximal to smaller distal diameters often creates a dilemma for optimal balloon sizing during percutaneous transluminal coronary angioplasty (PTCA). To demonstrate the need for new dilating catheters suitable for tapered coronary anatomy, 100 consecutive coronary arteries were measured by videodensitometry, 1 cm proximal and distal to the stenosis. In 23 arteries there was a 1 mm or greater taper and 19 arteries showed a 0.5 to 0.99 mm taper. Only 50 arteries showed a nearly uniform diameter at the site of the stenosis, and 8 arteries demonstrated reverse taper, i.e., distal was greater than proximal diameter. To avoid balloon size mismatch with significant tapering, decremental diameter balloon catheters were developed. Series I tapers from 3.5 to 3.0 mm and series II II from 3.0 to 2.5 mm over a balloon length of 25 mm. Tapered balloons were used in 80 patients with 94 tapered coronary arteries. Before PTCA, proximal, stenotic and distal mean diameters measured 3.6, 1.1 and 2.6 mm, respectively; after PTCA, proximal, stenotic and distal diameters measured 3.6, 2.8 and 2.5 mm, respectively, thus maintaining the natural tapering after effective dilatation. Only 2 arteries (2.1%) showed significant dissection, with no abrupt occlusions, and none requiring bypass surgery. In summary, decremental diameter balloon catheters provide optimal dilation in tapered arterial segments with few complications and offer a new approach to balloon sizing.