학술논문

Prediction of decrease in myocardial perfusion defect size and severity during a 3-month follow-up by the degree of acute resolution of electrocardiographic changes
Document Type
Report
Source
Journal of Electrocardiology. April, 2005, Vol. 38 Issue 2, p100, 6 p.
Subject
Language
English
ISSN
0022-0736
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jelectrocard.2004.10.003 Byline: Egle Kalinauskiene (a), Edvardas Vaicekavicius (a), Ilona Kulakiene (b) Abstract: Myocardial perfusion in infarct-related artery (IRA) distribution improves progressively until a few months after successful reperfusion therapy. We assessed the rate of electrocardiographic (ECG) stage dynamics to predict perfusion improvement after mechanical, thrombolytic, or spontaneous recanalization of IRA. Thirteen patients were divided into group A (n = 8, with [greater than or equal to]2 ECG stages per 2-day change rate) and group B (n = 5, no rapid change of ECG stages). There were no significant technetium Tc 99m sestamibi scintigraphic differences between the groups 3 days after recanalization; however, after 3 months, perfusion deficit size (2.8 [+ or -] 1.8 vs 4.8 [+ or -] 1.2, P [less than or equal to] .03) and severity (1.8 [+ or -] 0.9 vs 3.0 [+ or -] 0, P [less than or equal to] .03) were smaller in group A vs group B. The prediction sensitivity of the method was 87.5% for decrease in size and 100% for decrease in severity of perfusion defect; the specificity was 80% and 100%, respectively. A change rate of 2 or more ECG stages per 2 days predicts follow-up improvement of myocardial perfusion after IRA recanalization. Author Affiliation: (a) Institute of Cardiology, Kaunas University of Medicine, LT-50161 Kaunas, Lithuania (b) Department of Radiology, Kaunas University of Medicine, LT-50161 Kaunas, Lithuania