학술논문
Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis
Document Type
Report
Author
Suragani, Rajasekhar N V S; Cadena, Samuel M.; Cawley, Sharon M.; Sako, Dianne; Mitchell, Dianne; Li, Robert; Davies, Monique V.; Alexander, Mark J.; Devine, Matthew; Loveday, Kenneth S.; Underwood, Kathryn W.; Grinberg, Asya V.; Quisel, John D.; Chopra, Rajesh; Pearsall, R Scott; Seehra, Jasbir; Kumar, Ravindra
Source
Nature Medicine. April 1, 2014, p408, 10 p.
Subject
Language
English
ISSN
1078-8956
Abstract
Erythropoietin (EPO) stimulates proliferation of early-stage erythrocyte precursors and is widely used for the treatment of chronic anemia. However, several types of EPO-resistant anemia are characterized by defects in late-stage [...]