학술논문
Cloning of cDNA encoding Drosophila poly(ADP-ribose) polymerase: leucine zipper in the auto-modification domain
Document Type
Academic Journal
Author
Source
Proceedings of the National Academy of Sciences of the United States. April 15, 1993, Vol. 90 Issue 8, p3481, 5 p.
Subject
Language
ISSN
0027-8424
Abstract
A cDNA for Drosophila poly(ADP-ribose) polymerase (PARP) was isolated. Comparison of the sequence of this Drosophila PARP with those of the transcriptional factors and PARP sequences from other species indicated the presence of a leucine zipper in mammalian and chicken PARPs in the auto-modification domain. This motif might be responsible for protein-protein interaction between PARP and physiological acceptors.