학술논문

Rebound Weight Gain as Associated With High Plasma Norepinephrine Levels That Are Mediated Through Polymorphisms in the [beta]2-Adrenoceptor
Document Type
Report
Source
American Journal of Hypertension. Nov, 2005, Vol. 18 Issue 11, p1508, 9 p.
Subject
Noradrenaline -- Genetic aspects
Noradrenaline -- Physiological aspects
Leptin -- Genetic aspects
Leptin -- Physiological aspects
Peptide hormones -- Genetic aspects
Peptide hormones -- Physiological aspects
Obesity -- Genetic aspects
Obesity -- Physiological aspects
Language
English
ISSN
0895-7061
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjhyper.2005.05.006 Byline: Kazuko Masuo (a)(b), Tomohiro Katsuya (b), Hideki Kawaguchi (b), Yuxiao Fu (b), Hiromi Rakugi (b), Toshio Ogihara (b), Michael L. Tuck (c) Keywords: Rebound weight gain; weight loss resistance; sympathetic nerve activity; leptin; obesity; [beta]2-adrenoceptor polymorphisms Abstract: A successful weight loss program is essential treatment for obesity-related diseases, but it is well known that the majority of individuals do not succeed in weight loss maintenance. The present study evaluates hormonal mechanisms and the relationship of [beta]2-adrenoceptor polymorphisms involved in individuals who regain weight after initially successful weight loss. Author Affiliation: (a) Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia (b) Department of Geriatric Medicine, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan (c) Endocrinology and Metabolism Division, Sepulveda VA Medical Center and the David Geffen, UCLA School of Medicine, Los Angeles, California Article History: Received 5 April 2005; Revised 4 May 2005; Accepted 12 May 2005