학술논문
N-terminal mutations modulate yeast SNF1 protein kinase function
Document Type
Academic Journal
Source
Genetics. Nov 1992, Vol. 132 Issue 3, p639, 12 p. table
Subject
Language
ISSN
0016-6731
Abstract
A study was conducted to examine a mutation of an SNF1 protein kinase function. SNF1-G53R was isolated as an SNF4 suppressor. The study assumes that SNF1 protein kinase is needed for glucose-repressed gene expression after glucose deprivation. Results show that N-terminal mutations positively affect the protein kinase function and may interact with mutations other than SNF4. Findings also show that conserved threonine residue 210 is vital for SNF1 activity.