학술논문
T4 uptake into the perfused rat liver and liver T4 uptake in humans are inhibited by fructose
Document Type
Academic Journal
Author
Source
The American Journal of Physiology. May, 1994, Vol. 266 Issue 5, pE768, 8 p.
Subject
Language
ISSN
0002-9513
Abstract
Transport of iodothyronines in the liver is ATP-dependent and the transmembrane thyroxine (T4) uptake in the liver is controlled by intracellular energy reserves. Tissue uptake process that is carrier-mediated affects the intracellular metabolism and bioavailability of thyroxine. Fructase reduces the uptake of T4 tracer in the liver by inhibiting the transport of T4 in to intracellular region, while the uptake in the extraceullar pool is unaffected.