학술논문
An androgen receptor N-terminal domain antagonist for treating prostate cancer
Document Type
Report
Author
Source
Journal of Clinical Investigation. July 1, 2013, Vol. 123 Issue 7, p2948, 13 p.
Subject
Language
English
ISSN
0021-9738
Abstract
Hormone therapies for advanced prostate cancer target the androgen receptor (AR) ligand-binding domain (LBD), but these ultimately fail and the disease progresses to lethal castration-resistant prostate cancer (CRPC). The mechanisms [...]