학술논문
Aspects of Psychological Stress in Success of Parathyroid Allotransplantation
CASE REPORT
CASE REPORT
Document Type
Academic Journal
Source
Experimed. April 2022, Vol. 12 Issue 1, p29, 4 p.
Subject
Language
English
Abstract
INTRODUCTION Hypoparathyroidism is an uncommon endocrine disorder related to hypocalcemia, hyperphosphatemia, and low levels of parathyroid hormone (PTH) in the blood (1). The extended or complicated thyroidectomy operations often result [...]
Parathyroid auto/allotransplant (PA) may be a valuable alternative In the treatment of permanent hypoparathyroidism which is defined by insufficient levels of parathyroid hormone (PTH). Here, we aimed to investigate a possible association between the PTH levels of the patients who had undergone PA and their psychological stress conditions. The three patients with hypoparathyroidism were reported before and after PA for three-month-follow-up period. The examinations of patients were assessed by biochemical parameters [intact PTH (iPTH), Ca, and P]. The anxiety and stress levels of patients were assessed by self-report measures: State-Trait Anxiety Inventory (STAI-S/T) and Perceived Stress Scale (PSS). Although iPTH levels of all patients had a tendency to increase after PA, one of the patients with a low level of anxiety and stress only reached the normal range of PTH levels. The recovery of the serum iPTH levels at month 1 post-PA was negatively correlated with PSS scores of patients (r =-0.999, p=0.028). The outcomes of this report showed for the first time that insufficient PTH release, even after PA, might be related to the stress level of patients. By taking all results into consideration, PTH could be speculated as a stress biomarker. Keywords: Parathyroid allotransplantation, parathyroid hormone, psychological stress, STAI, PSS
Parathyroid auto/allotransplant (PA) may be a valuable alternative In the treatment of permanent hypoparathyroidism which is defined by insufficient levels of parathyroid hormone (PTH). Here, we aimed to investigate a possible association between the PTH levels of the patients who had undergone PA and their psychological stress conditions. The three patients with hypoparathyroidism were reported before and after PA for three-month-follow-up period. The examinations of patients were assessed by biochemical parameters [intact PTH (iPTH), Ca, and P]. The anxiety and stress levels of patients were assessed by self-report measures: State-Trait Anxiety Inventory (STAI-S/T) and Perceived Stress Scale (PSS). Although iPTH levels of all patients had a tendency to increase after PA, one of the patients with a low level of anxiety and stress only reached the normal range of PTH levels. The recovery of the serum iPTH levels at month 1 post-PA was negatively correlated with PSS scores of patients (r =-0.999, p=0.028). The outcomes of this report showed for the first time that insufficient PTH release, even after PA, might be related to the stress level of patients. By taking all results into consideration, PTH could be speculated as a stress biomarker. Keywords: Parathyroid allotransplantation, parathyroid hormone, psychological stress, STAI, PSS