학술논문
Androgens and Morphologic Remodeling at Penile and Cardiovascular Levels: A Common Piece in Complicated Puzzles?
Document Type
Report
Author
Source
European Urology. August, 2009, Vol. 56 Issue 2, p309, 8 p.
Subject
Language
English
ISSN
0302-2838
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.eururo.2008.12.037 Byline: Vincenzo Mirone (a), Ciro Imbimbo (a), Ferdinando Fusco (a), Paolo Verze (a), Massimiliano Creta (a), Gianfranco Tajana (b) Keywords: Androgens; Endothelial cell; Penile remodeling; Smooth-muscle cell; Vascular remodeling Abstract: Epidemiologic data demonstrate a protective role by normal androgen levels on cardiovascular health and erectile function. Low androgen levels are associated with erectile dysfunction and increased risk of cardiovascular diseases. Both conditions recognize as anatomic substrate a pathologic structural remodeling. Direct androgen effects on male external genitalia, vascular wall, and myocardium have been reported. Author Affiliation: (a) Department of Urology-University Federico II, Naples, Italy (b) Department of Pharmaceutical Science-University of Salerno, Salerno, Italy Article History: Accepted 25 December 2008