학술논문
miRNA panels as biomarkers for bladder cancer
Document Type
Report
Author
Source
Biomarkers in Medicine. June 2014, Vol. 8 Issue 5, p733, 14 p.
Subject
Language
English
ISSN
1752-0363
Abstract
Aim: Specific miRNA profiles have been identified for several samples from patients with bladder cancer. The results are not always congruent and partly contradictory. A comparison of published data was performed to select potential markers. Materials & methods: A literature search in PubMed identified 79 articles published prior to June 2013. Reports regarding the detection of miRNAs in urine and blood have rarely been published; to date, nine respectively three articles are available. Results: The comparison of published data proved the utility of miRNAs as diagnostic and prognostic indicators of bladder cancer. In urine samples from bladder cancer patients, seven miRNAs were concordantly expressed with tumor tissues. Conclusion: Standardization is strictly required in pre-analytics and methods of miRNA measurements.
Author(s): Angelika Tölle [sup.[*]] [sup.aff1] , Nadine Ratert [sup.aff1] [sup.aff2] , Klaus Jung [sup.aff1] [sup.aff2] Keywords: biomarker; bladder cancer; miRNAs; serum; tissue; urine Background Characteristics of bladder cancer & the [...]
Author(s): Angelika Tölle [sup.[*]] [sup.aff1] , Nadine Ratert [sup.aff1] [sup.aff2] , Klaus Jung [sup.aff1] [sup.aff2] Keywords: biomarker; bladder cancer; miRNAs; serum; tissue; urine Background Characteristics of bladder cancer & the [...]