학술논문
Potential-dependent block of human delayed rectifier K+ channels by internal Na+
Document Type
Academic Journal
Source
American Journal of Physiology (Consolidated). April 1996, Vol. 270 Issue 4, pC1131, 14 p.
Subject
Language
ISSN
0002-9513
Abstract
Human neuroblastoma cells can immediately change the positive charge on their membranes by blocking the influx of potassium ions through ion channels. The rectification rate was measured to be faster than 400 microseconds and depends on the internal concentration of sodium ions. The higher the sodium concentration inside the cell the faster the potassium influx was blocked, producing a negative slope conductance along the membrane.