학술논문

Effects of occupational and nonoccupational factors on liver functions tests in workers exposed to solvent mixtures
Document Type
Periodical
Source
Archives of Environmental Health. July-August, 1997, Vol. 52 Issue 4, p270, 5 p.
Subject
Solvents -- Health aspects
Medicine, Industrial -- Analysis
Environmental issues
Health
Language
ISSN
0003-9896
Abstract
. A total of 368 workers from six paint-manufacturing factories participated in this study. The workers were classified according to type of exposure: direct, intermittent, and no exposure. The workers' liver-function tests were influenced greatly by gender, hepatitis B, alcohol and body mass index. Both the serum concentration and the odds of abnormality of total serum bile acids were elevated among the directly exposed group. The authors concluded that analysis of covariance should take into account occupational and nonoccupational factors on liver-function tests to avoid any errors. Total serum bile acids also indicated liver dysfunction from solvent exposure.
THE INCIDENCE of acute liver injury from hepatotoxic chemicals has been reduced in recent decades. Long-term, low-level, and/or interacting occupational and environmental exposures may produce liver injury,[1-2] but how to [...]