부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jevs.2009.02.006 Byline: Fernando Jose Gondim (a), Claudio Cesar Zoppi (b), Leonardo dos Reis Silveira (c), Lucia Pereira-da-Silva (d), Denise Vaz de Macedo (d) Abstract: The purpose of this study was to evaluate oxidative stress, antioxidant biomarkers, and performance during a multiday 210-km endurance race. Nine endurance athlete horses participated in this study. Samples were always taken at the same times of day, before the beginning of the race and after every day of competition. Analytic measurements included glutathione reductase (GR) and catalase activity, thiobarbituric acid-reactive substances (TBARs), and reactive carbonylated derivatives. Competition intensity was low, with an average speed of 12.56[+ or -]0.9 km/h. Four horses were unable to finish the race because of metabolic problems or fatigue. GR activity increased progressively (P < .001) throughout the competition, and TBARs showed a significant rise compared with baseline values (P < .01) but remained at the same levels throughout the 3 days of competition. Catalase and reactive carbonylated derivatives did not show any significant alterations in any time period. The best performance was obtained from horses who demonstrated higher GR capacity and/or lower TBAR concentration. In conclusion, redox status seems to modulate horses' performance in endurance races, but further studies are needed to better determine the adequate oxidant/antioxidant ratio to acquire optimal performance. Author Affiliation: (a) Empresa Brasileira de Pesquisa Agropecuaria, Brasilia, Brazil (b) Laboratorio de Pesquisa do Exercicio, Faculdade Social da Bahia, Salvador, Brazil (c) Escola de Educacao Fisica e Esportes, Universidade de Sao Paulo, Ribeirao Preto, Brazil (d) Laboratorio de Bioquimica do Exercicio, Departamento Bioquimica, Universidade Estadual de Campinas, Campinas, Brazil