학술논문
Anemia and atrial fibrillation as independent risk factors for new-onset chronic kidney disease: the TAMA-MED Project--CKD and AF
ORIGINAL ARTICLE
ORIGINAL ARTICLE
Document Type
Academic Journal
Author
Source
Clinical Kidney Journal. October 2021, Vol. 14 Issue 10, p2221, 6 p.
Subject
Language
English
ISSN
2048-8505
Abstract
INTRODUCTION Chronic kidney disease (CKD) patients are at risk of developing end-stage renal disease (ESRD), and the number of affected people is increasing worldwide, which poses a major health economic [...]
Background. Various risk factors have been identified for the new onset or rapid deterioration of chronic kidney disease (CKD). However, it is thought that many risk factors that have not yet been clarified remain. Methods. Based on the results of specific annual health checkups at Tama City (n = 18 383) in 2017 and 2018, we analyzed the factors that cause new-onset CKD and the risk factors that rapidly worsen renal function. For new-onset CKD, proteinuria and estimated glomerular filtration rate (eGFR) 25% less than the previous year. Results. Multivariate analysis showed that in addition to age and impaired glucose tolerance, anemia and atrial fibrillation (AF) were risk factors for the new appearance of proteinuria. Risk factors for a decrease in eGFR to 3. Conclusions. From the results of specific annual health checkups at Tama City, AF, anemia and hyperuricemia were identified as risk factors for new-onset CKD over a short period of 1 year. Anemia was also a factor for the rapid deterioration of kidney function in subjects with renal dysfunction. Keywords: anemia, atrial fibrillation, chronic kidney disease, hyperuricemia, specific annual health checkups
Background. Various risk factors have been identified for the new onset or rapid deterioration of chronic kidney disease (CKD). However, it is thought that many risk factors that have not yet been clarified remain. Methods. Based on the results of specific annual health checkups at Tama City (n = 18 383) in 2017 and 2018, we analyzed the factors that cause new-onset CKD and the risk factors that rapidly worsen renal function. For new-onset CKD, proteinuria and estimated glomerular filtration rate (eGFR) 25% less than the previous year. Results. Multivariate analysis showed that in addition to age and impaired glucose tolerance, anemia and atrial fibrillation (AF) were risk factors for the new appearance of proteinuria. Risk factors for a decrease in eGFR to 3. Conclusions. From the results of specific annual health checkups at Tama City, AF, anemia and hyperuricemia were identified as risk factors for new-onset CKD over a short period of 1 year. Anemia was also a factor for the rapid deterioration of kidney function in subjects with renal dysfunction. Keywords: anemia, atrial fibrillation, chronic kidney disease, hyperuricemia, specific annual health checkups