학술논문
Predictive Factors of Postoperative Pancreatic Fistula in Geriatric Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancy
CLINICAL PRACTICE ARTICLE
CLINICAL PRACTICE ARTICLE
Document Type
Academic Journal
Author
Source
Journal of the College of Physicians and Surgeons Pakistan. December 2023, Vol. 33 Issue 12, p1439, 6 p.
Subject
Language
English
ISSN
1022-386X
Abstract
INTRODUCTION Periampullary cancers are infrequent and have high mortality rates. (1) Their occurrence is rare, but it is elevated within the geriatric population. (2) Pancreatoduodenectomy (PD) stands as one of [...]
Objective: To identify predictive factors associated with the occurrence of postoperative pancreatic fistula (POPF) following pancreatoduodenectomy (PD) in an increasingly geriatric population. Study Design: Observational study. Place and Duration of the Study: Department of General Surgery, Inonu University, Malatya, Turkey, from January 2010 to April 2022. Methodology: Demographic and clinicopathological data of 74 geriatric patients who underwent PD for periampullary tumours in the clinic at Inonu University were retrieved from the patient database. POPF was defined and categorised based on the guidelines established by the International Study Group for Pancreatic Surgery (ISGPS). The patients were stratified into two cohorts of POPF and no POPF. Univariate and multivariate analyses were conducted to compare variables between the two groups. Results: The median age of the patient population was 72 (65-92) years, and 51 (68.9%) individuals were male. Among the 74 patients, 35 (47.3%) experienced POPF. In the multivariate analysis, hypertension (HT, p=0.012), Wirsung diameter Conclusion: In the context of geriatric patients undergoing PD, HT, intraoperative wirsung diameter Key Words: Elderly, Whipple Procedure, Anastomotic Leakage, Predictive Factor, Postoperative Pancreatic Fistula, Pancreatoduodenectomy.
Objective: To identify predictive factors associated with the occurrence of postoperative pancreatic fistula (POPF) following pancreatoduodenectomy (PD) in an increasingly geriatric population. Study Design: Observational study. Place and Duration of the Study: Department of General Surgery, Inonu University, Malatya, Turkey, from January 2010 to April 2022. Methodology: Demographic and clinicopathological data of 74 geriatric patients who underwent PD for periampullary tumours in the clinic at Inonu University were retrieved from the patient database. POPF was defined and categorised based on the guidelines established by the International Study Group for Pancreatic Surgery (ISGPS). The patients were stratified into two cohorts of POPF and no POPF. Univariate and multivariate analyses were conducted to compare variables between the two groups. Results: The median age of the patient population was 72 (65-92) years, and 51 (68.9%) individuals were male. Among the 74 patients, 35 (47.3%) experienced POPF. In the multivariate analysis, hypertension (HT, p=0.012), Wirsung diameter Conclusion: In the context of geriatric patients undergoing PD, HT, intraoperative wirsung diameter Key Words: Elderly, Whipple Procedure, Anastomotic Leakage, Predictive Factor, Postoperative Pancreatic Fistula, Pancreatoduodenectomy.