학술논문
Renal hepatitis C in the absence of detectable serum or hepatic virus
Document Type
Report
Source
Liver International. July, 2008, Vol. 28 Issue 6, p889, 3 p.
Subject
Language
English
ISSN
1478-3223
Abstract
To purchase or authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1478-3231.2008.01672.x Byline: Andrew J. Fowell (1), Nicholas Sheron (1), William M. C. Rosenberg (2) Keywords: Glomerulonephritis; hepatitis C; polymerase chain reaction Abstract: Abstract We report an apparently unique case where hepatitis C virus (HCV) RNA was identified in renal tissue from a patient with membranoproliferative glomerulonephritis and treated chronic hepatitis C, despite the absence of detectable virus in the serum or liver (COBAS Amplicor qualitative assay, lower limit of detection 50 IU/ml). The implications of this finding are discussed, with particular reference to current concepts regarding 'occult' hepatitis C infection. Author Affiliation: (1) Liver Research Group, Division of Infection, Inflammation and Repair, Southampton General Hospital, University of Southampton, Southampton, UK (2) Institute of Hepatology, University College London, London, UK Article History: Received 27 July 2007Accepted 02 December 2007 Article note: Correspondence, Dr Andrew J. Fowell, Liver Research Group, Division of Infection, Inflammation and Repair, Southampton General Hospital, University of Southampton, Mailpoint 811, Tremona Road, Southampton, SO16 6YD, UK, Tel: +44 23 8079 8970, Fax: +44 23 8079 8519, e-mail: afowell@hotmail.com