학술논문
Adiponectin levels and genotype: a potential regulator of life span in humans
Document Type
Clinical report
Author abstract
Author abstract
Author
Source
The Journals of Gerontology, Series A. May, 2008, Vol. 63 Issue 5, p447, 7 p.
Subject
Language
English
ISSN
1079-5006
Abstract
Although caloric restriction in numerous models extends life, longevity in humans is suggested to be limited by the increased prevalence of obesity. Adiponectin, a fat-derived peptide, has a protective role against age-related disease, and thus is an excellent candidate gene for longevity. We studied adiponectin levels in centenarians (n = 118), their offspring (n = 228), and unrelated participants Key Words: Adiponectin--Genetics--Longevity--Metabolic syndrome--Cardiovascular disease.