학술논문
Persistent anti-gag, -nef, and -rev IgM levels as markers of the impaired functions of CD4(super +) T-helper lymphocytes during SIVmac251 infection of cynomolgus macaques
Document Type
Academic Journal
Author
Source
Journal of Acquired Immune Deficiency Syndromes (1999). Sept 1, 2005, Vol. 40 Issue 1, p1, 11 p.
Subject
Language
English
ISSN
1525-4135
Abstract
The antigen-specific immunoglobulin (Ig)M, IgG, and IgA humoral responses during the first 200 days of simian immunodeficiency viruses (SIV)mac251 infection in cynomolgus macaques are tested for correlation with the CD4(super +) T-cell related hematologic parameters. Strong correlations were observed between the preinfection CD4(super +) T-cell count and the parameters measured, suggesting the importance of preinfection immune status as a determinant of disease progression.