학술논문

Gestational weight gain and adiposity, fat distribution, metabolic profile, and blood pressure in offspring: the IDEFICS project
Document Type
Report
Source
International Journal of Obesity. July 1, 2013, Vol. 37 Issue 7, p914, 6 p.
Subject
Pregnancy -- Research -- Physiological aspects
Weight gain -- Research -- Health aspects
Adipose tissues -- Research -- Health aspects
Pregnant women -- Measurement
Body mass index -- Research -- Health aspects
Language
English
ISSN
0307-0565
Abstract
OBJECTIVE: To investigate the association between gestational weight gain (GWG) and total adiposity, body fat distribution, blood pressure (BP), and metabolic profile in offspring. DESIGN: Cross-sectional study. METHODS: Body mass index (BMI), waist, subscapular and tricipital skinfolds, and BP were measured and blood samples drawn in 12 775 children (aged 2-9 years) from the IDEFICS cohort. Overweight/obesity was defined by IOTF criteria. Parents filled in a questionnaire investigating child and familiar medical history and lifestyle. A section was dedicated to pregnancy history (including GWG). RESULTS: Anthropometric indices linearly and significantly increased across GWG tertiles (BMI z-score: tertile I = 0.08, 0.03-0.13; tertile II = 0.16, 0.12-0.21;tertile III = 0.34, 0.28-0.40, P International Journal of Obesity (2013) 37, 914-919; doi: 10.1038/ijo.2013.35; published online 9 April 2013 Keywords: gestational weight gain; perinatal factors; childhood obesity; offspring BMI; offspring metabolic profile; offspring blood pressure
INTRODUCTION The role of intrauterine environment in the future development of disease in offspring is an issue of extreme interest. So far, gestational weight gain (GWG) has been considered as [...]