학술논문
Epidemiological profile of head and neck cancers at a Tertiary Care Hospital
ORIGINAL ARTICLE
ORIGINAL ARTICLE
Document Type
Academic Journal
Author
Source
Journal of Evolution of Medical and Dental Sciences. October 12, 2015, Vol. 4 Issue 82, p14285, 9 p.
Subject
Language
English
ISSN
2278-4748
Abstract
INTRODUCTION: Head and neck cancer is the fifth most common malignancy globally among adults, (1) and comprises 5% of all malignancies worldwide. (2) Worldwide head and neck cancer statistics indicate [...]
Head and neck cancer is the fifth most common malignancy globally among adults and comprises 5% of all malignancies worldwide. There is scarcity of data regarding the clinico epidemiological profile of head and neck carcinomas in our population. The demographic presentation & exact prevalence of these malignancies in our population is not known. AIMS & OBJECTIVES: To study the clinico-epidemiological profile of head and Neck carcinoma in Kashmiri ethnic population of India. MATERIAL & METHODS: This study was conducted at Cancer center at SMHS Srinagar, J & K, India from 2012 to 2014. The study included total of 106 patients with Head and Neck Squamous Cell Carcinoma (HNSCC) registered with the department from 2012 to 2014. It was a prospective and retrospective study. Patients having histopathological (HPE) confirmation of the disease were enrolled for the study. All the demographic & clinical details of the recruited patients were studied thoroughly including history, physical examination, investigations and mode of treatment. RESULTS: Male to female ratio was 2.7:1. The mean age was 55.3 years. Among both males and females, the highest incidence of HNSCC was seen within the age group of 51-60 years. The most common primary site of disease was Oral Cavity-36(33.96%), Larynx-28 (26.41%), Pharynx in 16 (15.09%), Nasopharynx in 10 (9.43%), Sinonasal in 10 (9.43%), and Tonsil in 6 cases (5.66%). Patients usually presented with advanced stage of disease {(Stage III, IV- (64.15%) 68 versus stage I, II-(35.84%) 38}. Tobacco consumption in any form was present in 89% of our population. Lack of balanced diet (28%) and poor dental hygiene (50%) and belonging to low socioeconomic class (57%) were also thought to be significant factors for the disease burden. Most of our patients were treated with surgery followed by adjuvant chemo-radiotherapy (37.73%), chemo and radiotherapy (28.31%), radiotherapy alone (16.98%) & surgery alone (9.4%). CONCLUSION: Cancers of oral cavity and larynx are most common head & neck carcinoma in our population. Male Sex, tobacco consumption, lack of balanced diet & poor orodental hygiene are significantly associated with head and neck carcinoma in our population. KEYWORDS: Head and neck carcinoma, Kashmiri population.
Head and neck cancer is the fifth most common malignancy globally among adults and comprises 5% of all malignancies worldwide. There is scarcity of data regarding the clinico epidemiological profile of head and neck carcinomas in our population. The demographic presentation & exact prevalence of these malignancies in our population is not known. AIMS & OBJECTIVES: To study the clinico-epidemiological profile of head and Neck carcinoma in Kashmiri ethnic population of India. MATERIAL & METHODS: This study was conducted at Cancer center at SMHS Srinagar, J & K, India from 2012 to 2014. The study included total of 106 patients with Head and Neck Squamous Cell Carcinoma (HNSCC) registered with the department from 2012 to 2014. It was a prospective and retrospective study. Patients having histopathological (HPE) confirmation of the disease were enrolled for the study. All the demographic & clinical details of the recruited patients were studied thoroughly including history, physical examination, investigations and mode of treatment. RESULTS: Male to female ratio was 2.7:1. The mean age was 55.3 years. Among both males and females, the highest incidence of HNSCC was seen within the age group of 51-60 years. The most common primary site of disease was Oral Cavity-36(33.96%), Larynx-28 (26.41%), Pharynx in 16 (15.09%), Nasopharynx in 10 (9.43%), Sinonasal in 10 (9.43%), and Tonsil in 6 cases (5.66%). Patients usually presented with advanced stage of disease {(Stage III, IV- (64.15%) 68 versus stage I, II-(35.84%) 38}. Tobacco consumption in any form was present in 89% of our population. Lack of balanced diet (28%) and poor dental hygiene (50%) and belonging to low socioeconomic class (57%) were also thought to be significant factors for the disease burden. Most of our patients were treated with surgery followed by adjuvant chemo-radiotherapy (37.73%), chemo and radiotherapy (28.31%), radiotherapy alone (16.98%) & surgery alone (9.4%). CONCLUSION: Cancers of oral cavity and larynx are most common head & neck carcinoma in our population. Male Sex, tobacco consumption, lack of balanced diet & poor orodental hygiene are significantly associated with head and neck carcinoma in our population. KEYWORDS: Head and neck carcinoma, Kashmiri population.