부산대학교 도서관

Background: Surgical wound infection continues to consume a considerable portion of health care finance. Even though the complete elimination of wound infections is not possible, a reduction of observed wound infection rate to a minimum level could have marked benefits in terms of both patients comfort and resources used . As many surgeons believe that routine culture of peritoneal fluid in patients of secondary peritonitis offer no useful information & no clinical benefits, not too many studies had been done to support the utility of peritoneal fluid culture as a important parameter in preventing SSI.. This study was aimed to study relevance of peritoneal fluid culture in relation to its impact on surgical site infections and to know the most common organism associated with peritonitis & SSI with their antibiotic sensitivity in our hospital. Also to know if any correlation present between organism isolated from peritoneal fluid & organism isolated from pus from wound. Materials and Methods: A prospective & correlational study was conducted on 100 patients undergoing emergency laparotomy for perforation peritonitis. Samples from peritoneal fluid intraoperatively and discharge from infected post operative wound collected using a sterile swab and studied for identification of isolates by Gram stains and culture growth followed by in vitro antibiotic susceptibility testing performed by disc diffusion method. Results: SSI was more in Patients having positive peritoneal fluid culture (77.6%) but no positive correlation was found between the organism isolated from peritoneal fluid & organism isolated from pus from wound. E.coli was the most common organism isolated from peritonealfluid (75.8%) & klebsiella was the most common organism associated with surgical site infections (81.2%) in patients undergoing emergency laparotomy for perforation peritonitis & is resistant to most of the antibiotics supplied in our hospital set up. Conclusion: Though the incidence of SSI was more in Patients having positive peritoneal fluid culture but no positive correlation was found between the organism isolated from peritoneal fluid & organism isolated from pus from wound that means organism associated with peritonitis was later on not found to be causing SSI in the same patients. Routine culture & sensitivity of peritoneal fluid just give spectrum of data for starting antibiotics in early post- op period. Keywords: Routine Culture & Sensitivity, Peritoneal fluid, Antibiotics, Surgical Site Infection [SSI].
INTRODUCTION As many surgeons believe that routine culture of peritoneal fluid in patients of secondary peritonitis offer no useful information & no clinical benefits, not too many studies had been [...]