부산대학교 도서관

Objective To evaluate possible associations between cardiovascular autonomic dysfunction and peripheral artery disease (PAD) in patients with type 2 diabetes mellitus. Research design and methods In this cross-sectional study, 67 patients with type 2 diabetes were included. PAD was identified by Doppler ultrasonography: systolic ankle-brachial pressure index Results Patients with PAD (n = 30) had longer diabetes duration, higher systolic blood pressure (BP), waist-to-hip ratio, HbA1C test, and urinary albumin excretion (UAE) than patients without PAD. Most HRV indices in time domain were lower in patients with than without PAD. These patients also had lower PSA indices (LF=0.19[+ or -]0.07 vs. 0.29[+ or -]0.11 n.u.; LF/HF ratio=1.98[+ or -]0.9 vs. 3.35[+ or -]1.83; P Conclusion In conclusion, patients with type 2 diabetes with PAD had lower HRV indices than patients without PAD, reflecting a dysfunction of cardiovascular autonomic modulation. Keywords: Diabetes, Diabetic neuropathy, Autonomic neuropathy
Author(s): Luís Henrique Canani[sup.1] , Eduardo Copstein[sup.1] , Miriam Pecis[sup.1] , Rogñrio Friedman[sup.1] , Cristiane Bauermann Leitão[sup.1] , Mirela Jobim Azevedo[sup.1] , Cristina Triches[sup.1] , Dimitris Rucks Varvaki Rados[sup.1] , [...]