부산대학교 도서관

Byline: Christine Klein (1), Detlef Kompf (1), Ulrich Pulkowski (1), Andreas Moser (1), Peter Vieregge (1) Keywords: Key words Parkinson's disease; Hallucinations; Dementia; Psychosis; Aging Abstract: In a hospital-based case-control study 29 patients with idiopathic Parkinson's disease (PD) and visual hallucinations (VH) were compared with 58 PD patients matched for age and disease duration, but without VH. VH patients had more frequently sleep disturbances and dementia, higher PD-related disability (Schwab-England scale), and took selegiline more frequently as an anti-Parkinsonian drug. The patient groups did not differ in age at PD onset, Webster score, treatment duration, dosage of any anti-Parkinsonian drug, frequency of levodopa-associated movement disorders, or measures on brain CT. After a median follow-up period of 27 months more VH patients had developed wearing-off and freezing phenomena, while their scores in the Mini Mental State Examination were lower. Nursing home placement during the follow-up period was associated with higher PD-related disability in VH patients. Author Affiliation: (1) Department of Neurology, Medical University, Ratzeburger Allee 160, D-23538 Lubeck, Germany Tel.: +49-451-500-2928, Fax: +49-451-500-2489, DE Article note: Received: 15 October 1996 Received in revised form: 24 February 1997 Accepted: 27 February 1997