학술논문
Effects of a Primary Care Antimicrobial Stewardship Program on Meticillin-Resistant Staphylococcus aureus Strains across a Region of Catalunya (Spain) over 5 Years
Document Type
Academic Journal
Author
Jover-Sáenz, Alfredo; Ramírez-Hidalgo, María; Bellés Bellés, Alba; Ribes Murillo, Esther; Batlle Bosch, Meritxell; Ribé Miró, Anna; Mari López, Alba; Cayado Cabanillas, José; Piqué Palacín, Neus; Garrido-Calvo, Sònia; Ortiz Valls, Mireia; Gracia Vilas, María Isabel; Gros Navés, Laura; Javierre Caudevilla, María Jesús; Montull Navarro, Lidia; Bañeres Argiles, Cecilia; Vaqué Castilla, Pilar; Ichart Tomás, José Javier; Saura Codina, Mireia; Andreu Mayor, Ester; Martorell Solé, Roser; Vena Martínez, Ana; Albalad Samper, José Manuel; Cano Marrón, Susana; Soler Elcacho, Cristina; Rodríguez Garrocho, Andrés; Terrer Manrique, Gemma; Solé Curcó, Antoni; Escuin, David de la Rica; Estadella Servalls, María José; Figueres Farreny, Ana M.; Montaña Esteban, Luís Miguel; Sanz Borrell, Lidia; Morales Valle, Arancha; Pallerola Planes, Mercè; Hamadi, Aly; Pujol Aymerich, Francesc; Toribio Redondo, Francisca; Urgelés Castillón, María Cruz; Valgañon Palacios, Juan; Olivart Parejo, Marc; Torres-Puig-gros, Joan
Source
Antibiotics. January 2024, Vol. 13 Issue 1
Subject
Language
English
ISSN
2079-6382
Abstract
Author(s): Alfredo Jover-Sáenz (corresponding author) [1,*]; María Ramírez-Hidalgo [1]; Alba Bellés Bellés [2]; Esther Ribes Murillo [3]; Meritxell Batlle Bosch [4]; Anna Ribé Miró [4]; Alba Mari López [5]; José [...]
Primary care antimicrobial stewardship program (ASP) interventions can reduce the over-prescription of unnecessary antibiotics, but the impact on the reduction in bacterial resistance is less known, and there is a lack of available data. We implemented a prolonged educational counseling ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, which was compared to a pre-intervention period, a significant reduction in antibiotic prescriptions occurred, particularly those associated with greater harmful effects and resistance selection. There was also a decrease in methicillin-resistant Staphylococcus aureus (MRSA) strains and in their co-resistance to other antibiotics, particularly those with an ecological impact.
Primary care antimicrobial stewardship program (ASP) interventions can reduce the over-prescription of unnecessary antibiotics, but the impact on the reduction in bacterial resistance is less known, and there is a lack of available data. We implemented a prolonged educational counseling ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, which was compared to a pre-intervention period, a significant reduction in antibiotic prescriptions occurred, particularly those associated with greater harmful effects and resistance selection. There was also a decrease in methicillin-resistant Staphylococcus aureus (MRSA) strains and in their co-resistance to other antibiotics, particularly those with an ecological impact.