학술논문
IODINE STATUS AND THYROID FUNCTION IN LACTATING WOMEN AND INFANTS - A SURVEY IN THE ZAGREB AREA, CROATIA
Original Scientific Paper
Original Scientific Paper
Document Type
Report
Author
Source
Acta Clinica Croatica. June 2021, Vol. 60 Issue 2, p259, 9 p.
Subject
Language
English
ISSN
0353-9466
Abstract
Introduction Iodine is an essential micronutrient and important component of thyroid hormones. Thyroid hormones are crucial for thermal and metabolic regulation, growth, development and function of many tissues, among which [...]
Lactating women (LW) and infants have high dietary iodine requirements and are at risk of iodine deficiency. The aim of the study was to assess iodine status and thyroid function in LW and their breastfed infants in Zagreb, Croatia. The study included 133 LW and breastfed infant pairs. Urinary iodine concentration (UIC) and thyroid function parameters were measured in all subjects. In LW, breast milk iodine concentration (BMIC) was measured and iodine and salt rich food frequency questionnaire data were collected. Results of analysis indicated that 99.2% of the LW used iodized salt in household and 20.4% used iodine-containing vitamin and mineral supplements. Median (IQR) UIC was 75 [micro]g/L (19.0-180.5 [micro]g/L) in LW and 234 [micro]g/L (151.0-367.5 [micro]g/L) in infants, whereas BMIC was 121 [micro]g/kg (87.8-170.8 [micro]g/kg). Multivariate regression analysis revealed BMIC to be a significant predictor of infant UIC (p Key words: Breastfeeding; Infants; Iodine; Thyroglobulin; Thyroid hormones
Lactating women (LW) and infants have high dietary iodine requirements and are at risk of iodine deficiency. The aim of the study was to assess iodine status and thyroid function in LW and their breastfed infants in Zagreb, Croatia. The study included 133 LW and breastfed infant pairs. Urinary iodine concentration (UIC) and thyroid function parameters were measured in all subjects. In LW, breast milk iodine concentration (BMIC) was measured and iodine and salt rich food frequency questionnaire data were collected. Results of analysis indicated that 99.2% of the LW used iodized salt in household and 20.4% used iodine-containing vitamin and mineral supplements. Median (IQR) UIC was 75 [micro]g/L (19.0-180.5 [micro]g/L) in LW and 234 [micro]g/L (151.0-367.5 [micro]g/L) in infants, whereas BMIC was 121 [micro]g/kg (87.8-170.8 [micro]g/kg). Multivariate regression analysis revealed BMIC to be a significant predictor of infant UIC (p Key words: Breastfeeding; Infants; Iodine; Thyroglobulin; Thyroid hormones