학술논문
Factors associated with hantavirus infection in a wild host rodent from Cholila, Chubut Province, Argentina
Original investigation
Original investigation
Document Type
Academic Journal
Author
Source
Mammalian Biology. January 2018, Vol. 88 Issue 1, p107, 7 p.
Subject
Language
English
ISSN
1616-5047
Abstract
Introduction Hantavirus pulmonary syndrome (HPS) is an acute respiratory illness in humans, caused by some members of the genus Hantavirus, family Bunyaviridae. Each distinct form of the virus is closely [...]
Andes virus (ANDV) is a hantavirus hosted by the sigmodontine rodent Oligoryzomys longicaudatus in southern Argentina, where it is responsible for most cases of hantavirus pulmonary syndrome (HPS). The purpose of this study is to elucidate the biological and ecological characteristics of the host that increase the probability of ANDV infection in a O. longicaudatus population. The study was performed from spring 2003 to winter 2008 at Cholila, Chubut Province, Argentina. Rodent populations were sampled in four habitat types. Species, sex, body measurements (mass, body and tail length) and presence of wounds were recorded and blood samples for seroprevalence determination were obtained from the retroorbital sinus. Logistic regression models were applied to identify variables associated with the probability of infection of an individual. The most parsimonious model included sex, mass, body size and wounds as explanatory variables. Our results suggest that population structure and composition (age and sex) of O. longicaudatus should be considered as fundamental indicators to model the probability that infection with ANDV appears and/or persists in a population. A high Odds ratio value also showed the presence of wounds as an important feature in the infection model. Keywords: Andes virus Antibody prevalence Virus transmission Age Sex Wounds
Andes virus (ANDV) is a hantavirus hosted by the sigmodontine rodent Oligoryzomys longicaudatus in southern Argentina, where it is responsible for most cases of hantavirus pulmonary syndrome (HPS). The purpose of this study is to elucidate the biological and ecological characteristics of the host that increase the probability of ANDV infection in a O. longicaudatus population. The study was performed from spring 2003 to winter 2008 at Cholila, Chubut Province, Argentina. Rodent populations were sampled in four habitat types. Species, sex, body measurements (mass, body and tail length) and presence of wounds were recorded and blood samples for seroprevalence determination were obtained from the retroorbital sinus. Logistic regression models were applied to identify variables associated with the probability of infection of an individual. The most parsimonious model included sex, mass, body size and wounds as explanatory variables. Our results suggest that population structure and composition (age and sex) of O. longicaudatus should be considered as fundamental indicators to model the probability that infection with ANDV appears and/or persists in a population. A high Odds ratio value also showed the presence of wounds as an important feature in the infection model. Keywords: Andes virus Antibody prevalence Virus transmission Age Sex Wounds