학술논문
'Prostate Abscess' as the Initial Manifestation of Granulomatosis with Polyangiitis (Wegener's Granulomatosis)
Document Type
Clinical report
Author
Source
Urologia Internationalis. February 1, 2016, Vol. 96 Issue 2, p244, 3 p.
Subject
Language
English
ISSN
0042-1138
Abstract
Author(s): Sotirios Tsiodras; Garyfalia Poulakou; Konstantinos Leventakos; Helen Panopoulou; Antonia Elezoglou; Kassiani Manoloudaki; Michail Chrisofos; George Petrikkos; Ioannis G. Panayiotides Introduction Initially described in 1939, Wegener's granulomatosis is currently included [...]
Prostatic involvement in granulomatosis with polyangiitis (GWP), formerly known as Wegener's granulomatosis, is rare, mostly arising in the context of systemic involvement. Prostatic involvement as the first manifestation of this systemic disease is exceptionally rare. We hereby present the case of a 41-year-old male patient who underwent transurethral prostate resection for what was initially diagnosed as suppurative, focally necrotizing prostatitis. Prolonged postoperative fever that did not respond to various treatments, as well as the subsequent appearance of a left pleural effusion, a left upper pulmonary lobe lesion and cutaneous nodules, led to a reevaluation of histological slides which, along with the determination of serum c-ANCA/anti-PR3 antibody levels, established the diagnosis of GWP. Physicians, and especially urologists and infectious diseases specialists, should be aware of this rare association and consider GWP in the event of nonresolving prostatitis, especially when characteristic symptoms from other systems appear. Keywords: Prostate abscess, Granuloma, Prostate, Prostatitis, Granulomatosis with polyangiitis, Wegener's granulomatosis
Prostatic involvement in granulomatosis with polyangiitis (GWP), formerly known as Wegener's granulomatosis, is rare, mostly arising in the context of systemic involvement. Prostatic involvement as the first manifestation of this systemic disease is exceptionally rare. We hereby present the case of a 41-year-old male patient who underwent transurethral prostate resection for what was initially diagnosed as suppurative, focally necrotizing prostatitis. Prolonged postoperative fever that did not respond to various treatments, as well as the subsequent appearance of a left pleural effusion, a left upper pulmonary lobe lesion and cutaneous nodules, led to a reevaluation of histological slides which, along with the determination of serum c-ANCA/anti-PR3 antibody levels, established the diagnosis of GWP. Physicians, and especially urologists and infectious diseases specialists, should be aware of this rare association and consider GWP in the event of nonresolving prostatitis, especially when characteristic symptoms from other systems appear. Keywords: Prostate abscess, Granuloma, Prostate, Prostatitis, Granulomatosis with polyangiitis, Wegener's granulomatosis