학술논문
Our experience with sinonasal spindle cell variant of squamous-cell carcinoma: presentation of 2 cases and literature review
CASE REPORT: RHINOLOGY
CASE REPORT: RHINOLOGY
Document Type
Academic Journal
Source
B-ENT. June 2020, Vol. 16 Issue 2, p120, 4 p.
Subject
Language
English
Abstract
Introduction Case Presentation Spindle cell carcinoma (SpSCC) is a rare challenging variant of squamous cell carcinoma (SCC). SpSCC is predominantly located in the larynx (46.4%), followed by the hypopharynx and [...]
Spindle cell carcinoma (SpSCC) is a rare variant of squamous-cell carcinoma, concerning less than 3% of head and neck malignancies. SpSCC confined to the nasal cavity is even less frequently encountered, and there are only few case reports described. We present 2 cases of SpSCC of the nose and paranasal sinuses treated at our department in the past 5 years. The first case is of a 66-year-old man with sinonasal SpSCC, who presented with recurrent epistaxis from a mass confined to the left nasal cavity. Endoscopic excision of the mass was performed. The histopathological report showed a mixed tumor, mainly described as SpSCC. The second case is of an 82-year-old man who also presented with epistaxis. An exophytic mass originating from the anterior part of the nasal septum was discovered. The pathology report showed a diagnosis of SpSCC variant, and excision of the mass by means of lateral rhinotomy was performed. After 7 months of the operation, a metastatic lymph node at the ipsilateral neck was discovered, and the patient was subjected to lateral neck dissection and postoperative radiotherapy. In both cases, no evidence of residual or recurrent disease has been detected 2 years and 3 months post-treatment, respectively. Keywords: Cancer of the nose, head and neck squamous cell carcinoma, intranasal surgery, spindle cell
Spindle cell carcinoma (SpSCC) is a rare variant of squamous-cell carcinoma, concerning less than 3% of head and neck malignancies. SpSCC confined to the nasal cavity is even less frequently encountered, and there are only few case reports described. We present 2 cases of SpSCC of the nose and paranasal sinuses treated at our department in the past 5 years. The first case is of a 66-year-old man with sinonasal SpSCC, who presented with recurrent epistaxis from a mass confined to the left nasal cavity. Endoscopic excision of the mass was performed. The histopathological report showed a mixed tumor, mainly described as SpSCC. The second case is of an 82-year-old man who also presented with epistaxis. An exophytic mass originating from the anterior part of the nasal septum was discovered. The pathology report showed a diagnosis of SpSCC variant, and excision of the mass by means of lateral rhinotomy was performed. After 7 months of the operation, a metastatic lymph node at the ipsilateral neck was discovered, and the patient was subjected to lateral neck dissection and postoperative radiotherapy. In both cases, no evidence of residual or recurrent disease has been detected 2 years and 3 months post-treatment, respectively. Keywords: Cancer of the nose, head and neck squamous cell carcinoma, intranasal surgery, spindle cell