학술논문
Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport
Document Type
Academic Journal
Source
Proceedings of the National Academy of Sciences of the United States. Feb 28, 1995, Vol. 92 Issue 5, p1749, 5 p.
Subject
Language
ISSN
0027-8424
Abstract
Analysis of the amino acid sequence of RanGAP1, the GTPase activator for the nuclear Ras-related regulatory protein Ran, reveals its homology to murine Fug1 and to yeast Rna1p. This protein is associated with RNA processing and nucleocytoplasmic mRNA transport and both the protein and recombinant Rna1p promote RanGTPase activity. The Rna1p is primarily expressed in the cytoplasm.