학술논문
RanGAP1 induces GTPase activity of nuclear Ras-related Ran
Document Type
Academic Journal
Author
Source
Proceedings of the National Academy of Sciences of the United States. March 29, 1994, Vol. 91 Issue 7, p2587, 5 p.
Subject
Language
ISSN
0027-8424
Abstract
A nuclear homodimeric 65-kDa protein, RanGAP1, is the immediate exchange factor RCC1 and stimulates GTPase activity of Ran by a factor greater than three orders of magnitude. The protein Ran, which is related to the nuclear protein Ras, participates in cell cycle regulation and binds guanine nucleotide.